Tirzepatide
FDA-approved (Rx)Also known as: Mounjaro, Zepbound
Category: Weight & metabolic
Sold as:
Ameano Peptides: AMP-2P
Nexaph: NXP-2P
Dual GIP and GLP-1 receptor agonist. In trials it produced larger average weight loss than semaglutide.
What it's used for
- Chronic weight management
- Type 2 diabetes
- Obstructive sleep apnea in adults with obesity
Dosing
- Typical dose
- Label titration: 2.5 mg weekly for 4 weeks, then increase by 2.5 mg every 4 weeks as tolerated. Maintenance 5 to 15 mg weekly, maximum 15 mg.
- How often
- Once weekly
- Route
- Subcutaneous injection
- Cycle length
- Long-term
Build a dosing plan for Tirzepatide →
How to reconstitute and measure a dose → · About bacteriostatic water →
Possible side effects
- Nausea, diarrhea, vomiting, constipation
- Injection site reactions
- Rare: pancreatitis, gallbladder disease
Important: Prescription drug. Same thyroid tumor warning as semaglutide. Can reduce effectiveness of oral birth control during dose increases.